Anti-NMDA-receptor encephalitis was initially described as a paraneoplastic disorder in young women with ovarian teratoma. We report on a 3-year-old boy who developed anti-NMDA-receptor encephalitis one month after a respiratory infection.
Treg cells have a critical role in maintaining peripheral tolerance. In this Focus Review, Dominguez-Villar and Hafler describe how the instability and plasticity of Treg cells can contribute to the breakdown of tolerance and lead to autoimmune disease.
One of our goals at the AE Alliance is to distribute high-quality educational information for all who are touched by the illness. We have compiled a list of about a dozen articles that may be of interest.
It’s 2009, and a 24-year-old woman is living the dream life — working in New York City as a reporter, spending time with her new boyfriend, hanging out with friends.She starts experiencing minor problems, easily brushed-off issues like feeling off, ……
Hannah, from Dublin, was hospitalised days after her 21st birthday and treated for depression, anxiety and borderline psychosis before she was diagnosed her with Anti-NMDAR Encephalitis. This is her story.
Objective: To evaluate clinical, MRI, psychiatric, and neuropsychological outcomes in children with anti-NMDAR encephalitis. Background: Increased awareness of anti-NMDAR encephalitis has led to earlier diagnosis and initiation of immunotherapy, leading to improved clinical outcomes: 80% of…
In this Review, the authors discuss all aspects of immune-mediated disorders of the CNS in children, from the clinical features and treatment to pathological mechanisms and biomarkers, and outline priorities for collaborative research to develop precision medicine for these disorders.