Anti-NMDA Receptor Encephalitis Foundation Newsletter

The Hashimoto’s Encephalopathy SREAT Alliance (“HESA”)  is a 501(c)(3) nonprofit organization formed in 2012.  HESA’s purpose is collect, archive, and share information regarding Hashimoto’s Encephalopathy (“HE”), also known as Steroid Responsive Encephalopathy Associated with Thyroiditis…

 




This movie has the potential to save lives, writes Susannah Cahalan. And what’s more important than that?

 




The recent paradigm that autoimmune encephalitis is associated with autoantibodies that bind to conformational epitopes of cell surface antigens involved in neurotransmission has transformed the field of autoimmune neurology and created new biomarkers for the clinician to define treatable acquired…

 




Brain on Fire is a 2016 American-Canadian-Irish biographical drama film directed and written by Gerard Barrett, based on Susannah Cahalan’s memoir Brain on F…

 




Antibodies against N-methyl D-aspartate receptor (NMDAR) and other neuronal cell surface targets are recognised associations of immunotherapy-responsive autoimmune encephalitis. Initially, patients present with symptoms of behavioural change and psychosis, often subsequently developing seizures…

 




Neurology is a jungle, and for the unwary, a minefield. It perhaps has the most diverse number of complex diseases of all the medical specialties. Patients are often bewildered by neurological processes and procedures, ranging from the probing questions to the bizarre examination ritual.

 




We sometimes hear from patients and family members around the world. We are pleased to share this wonderful story of struggle and recovery written by a young girl’s father about their family’s experience with anti-NMDA receptor encephalitis.

 




Objective Hippocampal inflammation in anti-LGI1 encephalitis causes memory deficits, seizures and behavioural abnormalities. Recent findings suggest that extralimbic brain areas are additionally affected and that patients also suffer from non-limbic cognitive symptoms.

 




Multiple lines of evidence support the pathogenic role of neuroinflammation in psychiatric illness. While systemic autoimmune diseases are well-documented causes of neuropsychiatric disorders, synaptic autoimmune encephalitides with psychotic symptoms often go under-recognized.

 




LGI-1-IgG CSF index predicts worse neurological outcome
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