The Anti-NMDA Receptor Encephalitis Foundation Newsletter

This case series assesses the diseases misdiagnosed as autoimmune encephalitis and potential reasons for misdiagnosis.


Dr. Eoin Flanagan discusses his paper, “Autoimmune Encephalitis Misdiagnosis in Adults”. Show references: This podcast is sponsored by argenx. Visit for more information.


Sleep disorders in people with autoimmune encephalitis have received little attention,
probably overshadowed by the presence of other neurological and psychiatric symptoms
in this group of conditions.


Our study aimed to characterize seizure incidence and seizure outcome of pediatric
autoimmune encephalitis (AE) focusing on subgroup analysis based on antibody (Ab).


5-year-old Nathan Camargo had seizures at school before he was diagnosed with an autoimmune disorder…


The Romanian Association for Autoimmune Encephalitis (RAAE) starts its Webinar Series with an exciting event. We are honoured to have Mar Guasp MD, PhD who will give a talk on autoimmune encephalitis and its relevance to Psychiatry.


Anti-NMDA Receptor Encephalitis This is an autoimmune disorder in which antibodies attack NMDA (N-methyl D aspartate) type glutamate receptors at central neuronal synapses. Psychiatrists should have knowledge of this disorder and consider it in their differential diagnosis, as they are often the first to be consulted on these patients. Let’s begin by answering the following question first: Let’s begin by answering this question first: Which of the following feature is more consistent with NMDA Receptor Autoimmunity? Rapid Onset of Illness Fluctuating Catatonia Intolerance to Antipsychotics All of the above None of the above According to Josep Dalmau et al’s article published in Lancet Neurology (1), following criteria/acronym is helpful in identifying NMDA receptor autoimmunity: SEARCH For NMDA Receptor Autoimmunity S: Sleep Dysfunction E: Excitement, Disinhibition or Manic Behavior alternating with Depressive behavior A: Agitation or Aggression R: Rapid Onset C: Children & Young Adults Dominance H: History of Psychiatric Disease: Absent F: Fluctuating Catatonia N: Negative & Positive Symptoms at Presentation M: Memory Deficit D: Decreased Verbal Output or Mutism A: Antipsychotic Intolerance R: Rule out NMS A: Antibodies & Other Additional Tests (EEG, MRI or CSF) References:Dalmau J, Armangué T, Planagumà J, Radosevic M, Mannara F, Leypoldt F, Geis C, Lancaster E, Titulaer MJ, Rosenfeld MR, Graus F. An update on anti-NMDA receptor encephalitis for neurologists and psychiatrists: mechanisms and models. Lancet Neurol. 2019 Nov;18(11):1045-1057. (PMID: 31326280) Can You Identify Autoimmune Psychosis? Psychiatric News. (Published Online:4 Jan 2021) INTERESTED IN LEARNING MORE? Anti-NMDA Receptor Encephalitis: Diagnosis & Treatment This chapter will be summarized in the following sections: Demographics. Clinical features (phases). Duration of illness. Diagnosis. Treatment. Prognosis. Additional Important Clinical Tips. READ CHAPTER COFFEE CLUB DISCUSSION: Watch the following video discussion by a neurologist Dr. Seyed Mirsattari on: Anti-NMDA: What should you know as a Psychiatrist? WATCH DISCUSSION INTERESTED IN LEARNING MORE?JOIN PSYCHIATRY EDUCATION FORUM ACADEMY MEMBERSHIP This is a closed membership for medical professionals only.30+ Courses/Sections: Each chapter within these sections is of direct clinical relevance for your daily practice. Journal Club: we will post the most recently published psychiatry articles relevant to your daily clinical practice.Coffee Club: contain short discussions with clinical experts in the field of psychiatry.Clinical Case Discussions: Discussions of clinical cases from our daily clinical practice. Discussion Forum & Community: Connect with other medical professionals and discuss your difficult-to-treat clinical cases.Essentials of Inpatient Psychiatry Book: All chapters from this book are included in the academy sections. Goal: is to have all important clinically relevant topics in one place for ease of access. 20 Lessons Psychiatry Education Forum’s Journal Club 24 Lessons Psychiatry Education Forum’s Coffee Club 0 Lessons PEFA Academy Network 2 Lessons Clinical Case Discussions 0 Lessons PEFA Forum Discussions JOIN ACADEMY SUBSCRIBE TO OUR EMAIL NEWSLETTER: Subscribe to Email NewsletterFirst Name Last Name Email Join Email Newsletter Facebook Twitter Instagram Youtube Linkedin Share


The neurologist at Mayo Clinic in Jacksonville Florida talked about the significance of the ExTINGUISH trial, regarding care for patients with autoimmune encephalitis.[WATCH TIME: 4 minutes]…