The Anti-NMDA Receptor Encephalitis Foundation Newsletter

The Foundation is honoured to have been invited by The Texas Children’s Hospital to participate in their AE Day of Strength, for survivors and caregivers on Saturday, 27 July 2019, in Houston, Texas. Building on the success of last year’s event, titled AE Day of Hope, the theme this year will be Strength.This special event will bring together patients and their families affected by autoimmune encephalitis to connect with other affected families, to exchange stories of shared hardship and ways of coping, as well as learning about the latest updates in the field of neuro-immunology. No one should have to face the hardships of autoimmune encephalitis alone and what better way than to dedicate a day and shine a stark bright light on a group of diseases that few had heard of, until their loved-one was stricken. The global AE family is growing and strengthened thanks to the contribution, leadership and solidarity with patients and their families of The Texas Children’s Hospital. The Foundation’s founding president, Ms. Nesrin Shaheen is looking forward to making the keynote presentation and to meeting patients and their families. If you are in the Houston area or can travel, we would love to see you there.

 




The purpose of this review is to correlate autism with autoimmune dysfunction in the absence of an explanation for the etiology of autism spectrum disorder. Anti-N-methyl-D-aspartate receptor (anti-NMDAR) autoantibody is a typical synaptic protein that can bind to synaptic NMDA glutamate…

 




Anti N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune disorder and is considered to be one of the most common causes of encephalitis in children. Despite the fact that around half of all reported cases are of children, the number of …

 




Autoimmune Encephalitis is a disorder of the central nervous system caused by bodily substances, called antibodies. Antibodies normally help the body to…

 




We are excited to announce that Neurology® Neuroimmunology & Neuroinflammation (N2) has received our Impact Factor (7.353). We recognize that publishing in a journal with an impact factor is important to many authors, and we are excited to have the ability to receive and publish your contributions! We publish rigorously peer-reviewed open access reports of original research and in-depth reviews of topics in neuroimmunology & neuroinflammation. Clinical trials, instructive case reports, and small case series are also featured. Below are some highlights of what we have published over the past five years. We look forward to seeing your future work! Sincerely, Josep O. Dalmau, MD,PhD Editor, Neurology® Neuroimmunology & Neuroinflammation Highlights of Neurology® Neuroimmunology & Neuroinflammation from the past 5 years Zamvil SS, Slavin, AJ. Does MOG Ig-positive AQP4-seronegative opticospinal inflammatory disease justify a diagnosis of NMO spectrum disorder? Neurol Neuroimmunol Neuroinflamm 2015;1:262 https://nn.neurology.org/content/2/1/e62   Flanagan EP, Kotsenas AL, Britton JW et al. Basal ganglia T1 hyperintensity in LGI1-autoantibody faciobrachial dystonic seizures. Neurol Neuroimmunol Neuroinflamm 2015;2:e161 https://nn.neurology.org/content/2/6/e161   Ogawa R, Nakashima I, Takahashi T et al. MOG antibody-positive, benign, unilateral, cerebral cortical encephalitis with epilepsy. Neurol Neuroimmunol Neuroinflamm 2017;4:e322 https://nn.neurology.org/content/4/2/e322   Linnoila JJ, Binnicker MJ, Majed M, Klein CJ, McKeon A. CSF herpes virus and autoantibody profiles in the evaluation of encephalitis. Neurol Neuroimmunol Neuroinflamm 2016;3:e325 https://nn.neurology.org/content/3/4/e245   Baharnoori M, Lyons J, Dastagir A, Koralnik I, Stankiewicz JM.  onfatal PML in a patient with multiple sclerosis treated with dimethyl fumarate. Neurol Neuroimmunol Neuroinflamm 2016;3:e274 https://nn.neurology.org/content/3/5/e274   Gilden D, White T, Khmeleva N, Boyer PJ, Nagel MA. VZV in biopsy-positive and -negative giant cell arteritis: Analysis of 100+ temporal arteries. Neurol Neuroimmunol Neuroinflamm 2016;3:e216   Waters P, Woodhall M, O’Connor KC et al. MOG cell-based assay detects non-MS patients with inflammatory neurologic disease. Neurol Neuroimmunol Neuroinflamm 2015;2:e89 https://nn.neurology.org/content/2/3/e89   Spencer CM, Crabtree-Hartman EC, Lehmann-Horn K, Cree BAC, Zamvil SS. Reduction of CD8+ T lymphocytes in multiple sclerosis patients treated with dimethyl fumarate. Neurol Neuroimmunol Neuroinflamm 2015;2:e76 https://nn.neurology.org/content/2/3/e76   Azevedo CJ, Overton E, Khadka S et al. Early CNS neurodegeneration in radiologically isolated syndrome. Neurol Neuroimmunol Neuroinflamm 2015;2:e102 https://nn.neurology.org/content/2/3/e102   Zekeridou A, Lennon VA. Aquaporin-4 autoimmunity. Neurol Neuroimmunol Neuroinflamm 2015;2:e110 https://nn.neurology.org/content/2/4/e110   Galetta SL, Villoslada P, Levin N et al. Acute optic neuritis Unmet clinical needs and model for new therapies. Neurol Neuroimmunol Neuroinflamm 2015;2:e135 https://nn.neurology.org/content/2/4/e135   Bennett JL, O’Connor KC, Bar-Or A et al. B lymphocytes in neuromyelitis optica. Neurol Neuroimmunol  Neuroinflamm 2015;2:e104 https://nn.neurology.org/content/2/3/e104   Hacohen Y, Absoud M, Deiva K et al. Myelin oligodendrocyte glycoprotein antibodies are associated with a non-MS course in children. Neurol Neuroimmunol Neuroinflamm 2015;2:e81 https://nn.neurology.org/content/2/2/e81   Querol L, Rojas-Garcia R, Diaz-Manera J et al. Rituximab in treatment-resistant CIDP with antibodies against paranodal proteins. Neurol Neuroimmunol Neuroinflamm 2015;2:e149 https://nn.neurology.org/content/2/5/e149   Lejuste F, Thomas L, Picard G et al. Neuroleptic intolerance in patients with anti-NMDAR encephalitis. Neurol Neuroimmunol Neuroinflamm 2016;3:e280 https://nn.neurology.org/content/3/5/e280

 




Immunological mechanisms and therapy approaches in psychotic syndromes were recently supported by the discovery of autoantibody-associated limbic and non-limbic encephalitis. However, how clinical diagnostic procedures in psychiatry should be adapted to these new insights is still unclear.

 




J Neuropsychiatry Clin Neurosci. 2017 Summer;29(3):267-274. doi: 10.1176/appi.neuropsych.16050101. Epub 2017 Jan 25.Review; Systematic Review…

 




How caring for a three-year-old boy led Dr Anusha Yeshokumar to a career researching autoimmune neurology at Mount Sinai Hospital, New York.

 




The older man was unsteady on his feet and seemed to be talking nonstop. Then the seizures started, and his wife sounded the alarm.

 




Mult Scler J Exp Transl Clin. 2019 May 15;5(2):2055217319848463. doi: 10.1177/2055217319848463. eCollection 2019 Apr-Jun.

 




Please check out all the other patient testimonials on our website at the following link: https://www.antinmdafoundation.org/patient-stories/

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