The Anti-NMDA Receptor Encephalitis Foundation Newsletter

In celebration of World Encephalitis Day (WED), February 22, the Foundation is very pleased to release a trailer for the upcoming documentary on anti-NMDA receptor …Read More…

 




Neurocrit Care. 2019 Feb;30(1):207-215. doi: 10.1007/s12028-018-0599-4.

 




Perhaps it is that tension between undeniable differences and inevitable merging that has led to more recent calls for cross-disciplinary cooperation.

 




Immunotherapy with immune-checkpoint inhibitors (ICIs) is a new pillar in the treatment of cancer but can a have range of immune-related adverse effects, including some rare neurological toxicities that constitute paraneoplastic neurological syndromes (PNSs).

 




In their paper, Recken and colleagues, review the different autoantibodies, related clinical presentations and cancer associations and detection methods for autoantibodies. The review was comprehensive and nicely described most of the established antibodies.

 




Neurotherapeutics. 2019 Mar 13. doi: 10.1007/s13311-019-00725-4.[Epub ahead of print]…

 




‘Brain on Fire’ cases epitomize benefits of dual-trained doctors…

 




Ann Neurol. 2019 Mar 6. doi: 10.1002/ana.25460.[Epub ahead of print]…

 




Latest Medical News & Articles…

 




Doctors failed to catch Nadine McKenzie’s life-threatening encephalitis after she developed headaches and severe repeated panic attacks.

 




The Anti-NMDA Receptor Encephalitis Foundation, Inc.was established in Canada as a not-for profit-foundation on 26 October 201…

 




Paper published in Lancet Psychiaty may help with the accurate detection of this form of autoimmune encephalitis…

 




The Netflix drama ‘Brain on Fire is the story of a young woman in the U.S. who suddenly develops severe psychiatric symptoms. Some clever detective work reveals that she has a rare and mysterious condition causing brain inflammation.

 




It is critical to maintain a high index of suspicion for these conditions when evaluating a patient with demyelination to avoid delays in treatment.

 




The presence of autoantibodies against neuronal cell surface or synaptic proteins and their relationship to autoimmune encephalitis have recently been characterized. These autoantibodies have been also reported in other pathologic conditions; however, their role during sepsis is not known.

 




Chinese is perhaps the only hieroglyphic language still in use. The oldest Chinese
characters are found in oracle inscriptions on bones or tortoise shells of the Shang
Dynasty (16th–11th century BC), expressing concepts through hieroglyphic and ideographic
forms.

 




Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis was first reported in 2005 in four patients with ovarian teratomas; there have been many further cases reported since the antigen for the NMDAR antibody was confirmed in 2007.

 




Neurotherapeutics. 2019 Mar 13. doi: 10.1007/s13311-019-00725-4.[Epub ahead of print]…

 




Asian J Psychiatr. 2019 Feb 22;41:5-12. doi: 10.1016/j.ajp.2019.02.013.[Epub ahead of print]…

 




Encephalitis with anti-NMDAR antibodies (NMDAR-E) is a severe autoimmune neurological disorder, defined by a clinical presentation of encephalitis and the presence of IgG targeting the GluN1 subunit o…

 




As part of our My Brain and Me project, Lisa talks about life following encephalitis. Lisa, from Canada, shares her story of falling ill and living with auto…

 




UCL Discovery is UCL’s open access repository, showcasing and providing access to UCL research outputs from all UCL disciplines.

 




Antibodies against N-methyl D-aspartate receptor (NMDAR) and other neuronal cell surface targets are recognised associations of immunotherapy-responsive autoimmune encephalitis. Initially, patients present with symptoms of behavioural change and psychosis, often subsequently developing seizures…

 




Ann Neurol. 2019 Jan 24. doi: 10.1002/ana.25421.[Epub ahead of print]…

 




Ann Neurol. 2019 Jan 24. doi: 10.1002/ana.25421. [Epub ahead of print]