The Anti-NMDA Receptor Encephalitis Foundation Newsletter

Dr. Honnorat has more than 25 years of experience in the field of paraneoplastic neurological syndromes (PNS) and autoimmune encephalitis (AE). The topic of his presentations will be the role of genetics in autoimmune encephalitis (AE). He is head of the Department of Neuro-Oncology at the neurological hospital, Hospices Civils de Lyon and a team leader of the “Synaptopathies and Autoantibodies (SynatAc)” at the Institute NeuroMyoGene (UMR INSERM U1217, CNRS 5310). He is also chair of the French rare disease reference center “paraneoplastic neurological syndrome and autoimmune encephalitis” since 2007, which collects samples from all over France and provides care and follow-up for people with rare diseases. He has been working on PNS and AE for more than 25 years. His main work combines Basic and Clinical Research at multiple levels (patient’s cohorts; biological collections; cellular and animal models; biomarkers…) to explore the pathophysiologies of both brain tumors and neuro-inflammatory diseases and to detect specific autoantibodies as biomarkers of these diseases and as tools to understand synaptic functions.  We invite you to register today for what promises to be just one of the fascinating presentations of the conference.

The authors would like to correct some errors in the publication of the original article. The corrected and updated details are given below for your reading.

Here, we found a novel autoimmune encephalitis associated with anti-Ca_V α2δ antibody. Further analysis of the antibody in autoimmune encephalitis might promote the early diagnosis and treatment.

The rates of coexisting anti-NMDA receptor encephalitis and MOG antibody-associated encephalomyelitis may be underestimated.Clinical symptoms such as seizures and cognitive decline accompanied by atypical central nervous system demyelination serve as warning signs of possible coexisting anti-NMDA…

Objective Diagnosing autoimmune encephalitis (AIE) is difficult in patients with less fulminant diseases, like epilepsy. However, recognition is important, as patients require immunotherapy. This s…

Advances in autoimmune encephalitis studies in the past 10 years have led to the identification of new syndromes and biomarkers that have transformed the diagnostic approach to the disorder.The disorder or syndrome has been linked to a wide variety of pathologic processes associated with the neuron…

He was getting lost driving home from work. And he was having strange spasms. What was the cause?

The factors that predispose to relapse in patients recovering with autoimmune encephalitis (AE) are largely unknown, complicating efforts to distingui……

Abstract The contributors to persistent cognitive impairment and hippocampal atrophy in leucine‐rich glioma‐inactivated 1 antibody encephalitis (LGI1) patients are unknown. We evaluated whether tau…

The aim of this project is to improve biological collections of patients presenting rare neurological disorders with known or suspected autoimmune origin…